Trenadex 100 - Buy Trenbolone Acetate (Finaplix / finajet)

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Product Name: Trenadex Acetate
Substance: Trenbolone Acetate
Content: 10ml vial /100mg /1ml
Manufacturer: Sciroxx laboratories

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Data sheet

Active IngredientsTrenbolone Acetate
Route of AdministrationIntramuscular Injection

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Trenbolone: Overview, Characteristics, Benefits, and Effects

Overview

Trenbolone is a 19-nortestosterone steroid, also known as 19-nor. Steroids with the 19-nor structure are part of the nandrolone family, with the most well-known member being Nandrolone Decanoate, also known as Deca-Durabolin. Trenbolone is structurally very similar to Deca-Durabolin. As the name 19-nortestosterone suggests, a carbon at the 19 position of testosterone was removed to create this molecule. This modification enhances the anabolic activity of this family of molecules and reduces its androgenic impact.

Anabolic Activity

The alteration at the 19-carbon location enhances the molecule's affinity to the androgen receptor, thereby enhancing its anabolic properties, which directly potentiate protein synthesis and accumulation in muscle tissue. Trenbolone undergoes more changes to its molecule than Deca-Durabolin, particularly at the carbon c-11 and c-9 positions. In these positions, a hydrogen atom present in Deca was removed and replaced with a double bond between two carbons. The alteration at the c-11 position significantly enhances the anabolic activity of Trenbolone beyond the already enhanced anabolic activity of Deca-Durabolin compared to testosterone.

Furthermore, unlike testosterone and possibly other anabolic steroids which convert to estrogen, Trenbolone doesn't raise HGH (human growth hormone) levels. Instead, Trenbolone directly potentiates IGF-1 action. IGF-1 is the anabolic mediator of HGH and is considered the most anabolic hormone in the human body. Trenbolone enhances IGF-1 receptor proliferation and activity. This was proven when certain medicines that antagonize IGF-1 effects were given to animals treated with Trenbolone, resulting in diminished anabolic effects. Later animal models proved the involvement of Trenbolone in IGF-1 expression. Moreover, multiple studies on animals treated with Trenbolone suggest that one possible mechanism responsible for its ability to stimulate skeletal muscle hypertrophy may be through enhanced proliferation and differentiation of satellite cells, as a result of the increased sensitivity of these cells to IGF-I and FGF.

Androgenic Impact

Testosterone is converted in target androgenic tissues (such as the prostate and scalp) into dihydrotestosterone through an enzyme called 5-alpha reductase. Dihydrotestosterone is a much more potent androgen, which manifests in the pronounced androgenic activity of testosterone. The 19-nor steroids also interact with the enzyme 5-alpha reductase; however, they create much less potent androgen metabolites than dihydrotestosterone, hence their reduced androgenic impact compared to testosterone. In a drug like Deca Durabolin (Nandrolone Decanoate), the anabolic effects are much more pronounced than the androgenic effects, meaning its impact on muscle anabolism is higher than testosterone, while its impact on androgenic target tissues such as the prostate and scalp is lower.

As mentioned above, the alteration at the c-11 position significantly augments the anabolic activity of Trenbolone. However, these structural alterations also increase its androgenic impact, making Trenbolone more androgenic than Deca-Durabolin. Nonetheless, unlike testosterone, Trenbolone as a 19-nortestosterone is converted to less active metabolites in androgenic target tissues, maintaining a high anabolic/androgenic ratio. Overall, Trenbolone is rated as five times more anabolic than testosterone and about 30% less androgenic than testosterone. In comparison, Deca is about 2-3 times more anabolic than testosterone and about 3 times less androgenic.

Anti-Catabolic Effects

Continuing to investigate this trait of Trenbolone, it's important to mention that testosterone and its derivatives have both anabolic (muscle synthesis) effects and anti-catabolic effects (lowering protein degradation). In muscle tissue, both processes happen simultaneously, with protein synthesis always present concurrently with protein degradation processes. Scientific studies have shown that Trenbolone exhibits more pronounced anti-catabolic effects (lowering protein degradation) compared to testosterone. This mechanism is attributed to its potent ability to interact with corticosteroid receptors. Cortisol is the primary catabolic hormone in the body, responsible for protein degradation, especially in muscle tissue.

In this regard, it's interesting to note that a deep glance at the brochure of Deca-Durabolin by Organon reveals that to achieve the optimal effect with Deca-Durabolin, a surplus in calories and protein should be supplied. This is a basic pillar in any anabolic treatment. Multiple studies on Trenbolone in livestock have shown that it promotes distinct muscle growth even in the absence of a caloric surplus. This is associated with increased food efficiency, meaning the same amount of calories (and nitrogen/protein) yields much higher growth rates in calves, an interesting testimony to its anti-catabolic traits. Therefore, Trenbolone is a very effective agent even under catabolic conditions, making it highly desired during phases when the subject needs to lose weight but maintain muscle mass, strength, and performance at their peak.

Trenbolone and Estrogen:  "Sculpted muscle gains"

What makes Trenbolone particularly interesting as an anabolic agent, especially in bodybuilding, is the alteration in the c-9 bond. This change in its structure prevents any aromatization (conversion) to estrogen, resulting in far less water retention compared to both testosterone and Deca-Durabolin. This lack of estrogenic activity, combined with its powerful ability to bind to the androgen receptor, makes Trenbolone a much more potent steroid than Deca and testosterone, virtually eliminating all water gain. The majority of weight gained on this drug (at least in animal studies) is virtually all new, quality muscle.

Trenbolone and Its Impact on Progesterone, Prolactin, Serotonin, and Side Effects

Despite its exceptional anabolic characteristics, not everything is straightforward with Trenbolone. Trenbolone has been shown to have a high affinity for the progesterone receptor, even higher than progesterone itself, a female sex hormone. This interaction may lead to:

  • Gynecomastia: Development of breast tissue in males due to the progestogenic activity of Trenbolone. Progesterone can stimulate the mammary glands, and when combined with elevated estrogen levels, it can exacerbate this condition.
  • Sexual Dysfunction: Progestogenic steroids can sometimes lead to sexual dysfunction, including decreased libido and erectile dysfunction. This is because progesterone can negatively impact the hypothalamic-pituitary-gonadal (HPG) axis, reducing testosterone and other crucial androgens for normal sexual function.
  • Increased Prolactin Levels: While Trenbolone itself does not directly raise prolactin levels, its progestogenic activity can indirectly influence prolactin secretion. Elevated prolactin levels can lead to side effects such as lactation (galactorrhea) and further contribute to sexual dysfunction.
  • Mood Changes: Progestogenic steroids can affect mood and mental health. Users may experience mood swings, irritability, depression, or anxiety. These changes are likely due to progesterone's impact on the central nervous system.
  • Water Retention and Bloating: Although Trenbolone is known for not causing significant water retention due to lack of estrogen conversion, its progestogenic activity can still lead to some degree of water retention and "bloating" in certain individuals. Hence, it's usually advised to reduce Trenbolone usage at least a couple of weeks before competition days, whether as a fighter, track and field athlete, weightlifter, or bodybuilder.
  • Suppression of Natural Testosterone Production: All anabolic steroids, including Trenbolone, suppress natural testosterone production. The progestogenic effects can further exacerbate this suppression, leading to a significant reduction in endogenous testosterone levels. This can cause symptoms associated with low testosterone, such as fatigue, muscle loss, and mood disturbances.

Serotoninergic Effects

Treatment with 19-Nor AAS, including Trenbolone, can alter serotonin receptor density in animals, potentially explaining the association between Trenbolone use and changes in emotional states and behavior. This can manifest as heightened irritability, frustration, aggression, and, in extreme cases, episodes of violence. Impact on serotonin may also lead to insomnia, restless sleep, and disrupted sleep cycles reported by Trenbolone users.

Managing Progestogenic Side Effects

  • Aromatase Inhibitors: While Trenbolone itself does not aromatize, some users stack it with testosterone, which can increase estrogen levels. Using aromatase inhibitors can help manage estrogen levels and mitigate gynecomastia risk.
  • Dopamine Agonists: Medications like cabergoline or bromocriptine can help manage elevated prolactin levels and associated side effects.
  • Post-Cycle Therapy (PCT): Implementing a proper PCT regimen can help restore natural testosterone production and mitigate the suppressive effects of Trenbolone.
  • Regular Monitoring: Regular blood tests to monitor hormone levels can help detect and manage side effects early.

Combination with Other Steroids in a Cycle

As shown above, Trenbolone has a high anabolic/androgenic ratio, which by definition makes it an effective SARM (Selective Androgen Receptor Modulator). For the promotion of growth in livestock, Trenbolone is combined in many cases with estrogen for optimal results of sheer weight and muscle gains. Indeed, it's scientifically known that estrogen has a systemic anabolic effect through multiple mechanisms, as well as target receptors on muscle tissue. Male athletes are not livestock, of course, hence the addition of estrogen just for adding more muscle is not something to consider. However, the combination of Trenbolone with testosterone, which is converted to estrogen through a known mechanism, is a very favorable one for muscle growth. Trenbolone acetate combines very well with fast-acting testosterone esters such as testosterone propionate.

The lack of conversion of Trenbolone to an active dihydro derivative, like testosterone is converted to dihydrotestosterone, makes the addition of dihydrotestosterone-based products such as Masteron, Primobolan, and Proviron effective as well. In this regard, oral dihydrotestosterone derivatives such as Winstrol, Anavar, and Turinabol are also good choices. Note that oral steroids such as the aforementioned shouldn't be used for more than 4-6 weeks due to the stress they may put on the liver.

Dosage, Half-Life, and Administration

Trenbolone acetate contains the molecule of Trenbolone described in detail above, attached to an acetate ester. This ester determines the rate of absorption of Trenbolone in the serum and enables its dissolution in oily preparations for injection. It has a relatively short half-life of about 24-36 hours, necessitating injections at least every other day. Trenbolone acetate is recommended for beginners due to its relatively harsh nature. More advanced users will find Trenbolone acetate an almost irreplaceable part of their toolkit. The effective dosage of Trenbolone acetate is about 50-100 mg injected every day or every other day, thus the weekly dosage ranges between 175-500 mg and above for very advanced users.

Women should avoid Trenbolone acetate almost at any cost and under any circumstances.

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Trenadex 100 - Buy Trenbolone Acetate (Finaplix / finajet)

Trenadex 100 - Buy Trenbolone Acetate (Finaplix / finajet)

Product Name: Trenadex Acetate
Substance: Trenbolone Acetate
Content: 10ml vial /100mg /1ml
Manufacturer: Sciroxx laboratories

EU and international guaranteed delivery

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